Dose = (Desired / Have) × Vehicle
Example: Order: Amoxicillin 500 mg PO. Available: 250 mg/5 mL
Set up conversion factors to cancel units systematically.
Example: Order: Morphine 4 mg IV. Available: 10 mg/mL
mL/hr = Total Volume (mL) / Time (hours)
Example: Infuse 1000 mL NS over 8 hours
gtts/min = (Volume × Drop Factor) / (Time in minutes)
Drop factors: Macro = 10, 15, or 20 gtts/mL; Micro = 60 gtts/mL
Example: 1000 mL over 8 hours, drop factor 15
Dose = Weight (kg) × Dose (mg/kg)
Example: Patient weighs 70 kg. Order: Vancomycin 15 mg/kg
Always calculate the safe dose range and compare to the ordered dose.
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